UCAR (Unit for Clinical and Applied Research)

The mission of the Unit for Clinical and Applied Research (UCAR) is to enable all clinical research groups to achieve outstanding scientific results at the lowest possible administrative cost, through the coordination and expansion of its range of services. This should be achieved with optimum methodology both within the ethical and legal requirements of GCP (Good Clinical Practice) and the provisions of new human research legislation.

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The Unit for Clinical and Applied Research (UCAR) monitors the infrastructural and research staff resources and by coordinating and extending its range of services it enables the clinical research groups to achieve outstanding scientific results at the lowest possible administrative cost within the boundaries of ethical and legal requirements of GCP (Good Clinical Practice) and the provisions of new human research legislation. The unit is a central, internal relay station that has an overview of the clinical projects and developments of the University Clinic Balgrist and can give impulses for the extension, reduction, merging, cooperation and start of new multi disciplinary projects. The unit is in close contact with experimental research groups and fosters translation in both directions.

UCAR is structured into three sections: The science-administration section's main priority is focused on processes with ethics proposals as well as the clinic wide research databank system. The section also fosters the expansion of competences and specialisations of the scientific employees. The scientific-coordination section coordinates the standard operating procedures (SOP) and manages the internal and external studies register. The methodology section consults and supports the researchers - a priori - with the design of adequate studies, establishing the rules of scientific behavior and organising statistical consultations either with internal or external resources.

  • Goal:
    UCAR is a platform that unifies the processes of clinical research under the guidelines of GCP and HFG. It optimises the use of staff and infrastructural resources and fosters interdisciplinary cooperation to achieve outstanding research results.
  • Issues:
    The transfer of new findings from clinical and experimental research to patient treatment and benefit is the core goal of the University Clinic Balgrist. This includes the autonomous development or adoption of new knowledge and skills, the transfer to clinical practice and continuous review of the correctness and value of the new concepts, as well as the newly implemented measures. The execution of such clinical research is always associated with a large administrative effort and legislative challenges that can overburden the researchers.
  • Research:
  • Phases:
  • Budget:
    The main share of the costs are the due to research staff (research assistants / nurses). Other costs are incurred by the use of external services and the handling fees of ethic proposals.
  • Progress:

Embedment in Balgrist research

UCAR has been completely integrated into the clinical research of the clinic since its inception in 2014 and serves as a central administrative point. The services of UCAR are being used to an ever increasing amount by many departments of the University Clinic Balgrist. The research data base the UCAR manages is now very well established.

Innovation

UCAR provides impulses for innovation by merging research groups and intensifying their cooperation.

Prof. Dr. Jess Snedeker is Extraordinarius for Orthopedic Biomechanics at the University Zürich (University Clinic Balgrist, Laboratory for Orthopedic Biomechanics) and at the Eidgenössischen Technischen Hochschule Zürich (ETHZ, Institute for Biomechanics). He has headed the research laboratory for orthopedic biomechanics since 2006.

Apart from its fundamental research on the interaction between cells and biomaterial the laboratory of Prof. Snedecker has successfully investigated clinical challenges posed by orthopedics of the shoulder, knee, hand and foot in close cooperation with leading orthopedic surgeons at the University Clinic Balgrist.

The transfer of new findings from clinical and experimental research to patient treatment and clinical practice as well as the continuous review of the correctness and value of the new concepts have as a goal the best possible current and future treatment of patients which is a core goal of the University Clinic Balgrist. UCAR supports and simplifies the administrative implementation of clinical research.